Understanding Mefenamic Acid and Dicyclomine Hydrochloride Tablets IP| Myespas Tablet

Darshan Singh
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Mefenamic acid and Dicyclomine hydrochloride tablets: Uses, Dosage, Side Effects, and More..

Introduction:

Mefenamic Acid and Dicyclomine Hydrochloride Tablets IP are widely used and available over-the-counter medications in India. These tablets contain Mefenamic Acid 250mg which is a nonsteroidal anti-inflammatory drug (NSAID), and Dicyclomine Hydrochloride 10mg, a well-known antispasmodic agent. These drugs' combined properties offer a wide range of medical uses,  which focus on pain relief in the stomach and menstrual cramps. It provides instant relief from the pain associated with intestinal, biliary, and ureteric colic.
Understanding Mefenamic Acid and Dicyclomine Hydrochloride Tablets IP| Myespas Tablet


Overview of Mefenamic Acid:

Mefenamic Acid belongs to the NSAID category, renowned for its analgesic (pain-relieving) and antipyretic (fever-reducing) properties.

The mechanism of action of Mefenamic Acid is to inhibit the production of prostaglandins a chemical in the body that is responsible for pain and inflammation. As other NSAIDs work to stop pain Mefenamic Acid also follows a similar mechanism. 

Uses and Indications:

Mefenamic Acid and Dicyclomine Hydrochloride Tablets IP are commonly prescribed for different clinical symptoms. These tablets provide a potent aid in reducing stomach pain, especially generated by conditions like irritable bowel syndrome (IBS) or gastrointestinal spasms.

Additionally, these tablets are very helpful in managing menstrual cramp pain. 

Dosage and Administration:

Mefenamic Acid and Dicyclomine HCL tablets IP are covered in Schedule H Drug list prescription medicines, therefore these tablets should not be taken without the guidance of a medical professional. 

The dosage guidelines for these tablets may vary because of an individual's age, medical condition, and severity of symptoms.

Typically, for adults, the recommended dosage is prescribed by healthcare providers which may be one tablet twice a day.

For children below 14 years of age, dosage is determined based on weight and age, and instructions should be followed strictly for children's use.

MYESPAS TABLETS
Composition 
Mefenamic acid 250mg + Dicyclomine Hcl 10mg 

MYESPAS TABLET USES

Dicyclomine Hydrochloride and Mefenamic Acid Tablet are used to treat menstrual pain and colicky pain. It is also used to treat spasms of the intestines such as occur in irritable bowel syndrome.

Mechanism of Myespas Tablet working:

Myespas is a combination of  Dicyclomine Hydrochloride and Mefenamic Acid. Dicyclomine is an anticholinergic that relaxes the muscles in the stomach and gut (intestine). Dicyclomine stops sudden muscle contractions (spasms), thereby relieving cramps, pain, bloating, and discomfort.

Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the release of certain chemical messengers that cause abdominal pain and inflammation (swelling). In combination, they relieve menstrual cramps and colicky pain. Brand Name: MYESPAS

Side effects of Mefenamic and Dicyclomine tablets:

There are several types of side effects of Mefenamic and Dicyclomine Hcl tablets if they are not used under the guidance of a Health Professional. Since it is a Schedule H Drug prescription medication, it should not be used as self-medication. Some common side effects are as follows:
  • Ringing in ear
  • Dyspepsia
  • Constipation
  •  Itching
  • Dryness in mouth
  • Dizziness
  • Headache
  • Drowsiness
  • Nausea
  • Diarrhea

Contraindications and Precautions:

If you have a history of allergic reactions to NSAIDs, gastrointestinal issues, or certain blood disorders should avoid Mefenamic Acid and Dicyclomine Tablets IP. Patients taking medicines for liver, kidney, or heart diseases, should consult their doctor before starting the course of this tablet.

Drug Interactions:

Potential drug interactions may occur when Mefenamic Acid and Dicyclomine Hydrochloride Tablets IP are combined with other medications like blood thinners or certain antidepressants. Therefore, consulting your doctor before starting the course of any new medication is crucial to avoid adverse interactions.

Short Description:

Dosage Form: Tablets

Composition: Mefenamic acid 250mg + Dicyclomine Hcl 10mg + Simethicone 25mg

Packing : 10*10 alu alu

MRP: Rs. 45.00

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Laadic-MR Tablet: Diclofenac Potassium, Chlorzoxazone and Paracetamol Tablet.

Safety Measures:

To ensure safe usage, these tablets should be stored in a secure place, out of reach of children and away from excessive heat or moisture. 

For India:

Emergency Helplines:
 National Emergency Helpline: Dial 112 (toll-free)
Ambulance Services: Dial 108 (toll-free)

Specific Resources for Medical Emergencies: 
National Poisons Information Centre (NPIC): 1800-116-117 (toll-free)
Tel No.- 011-26589391, 26593677
United States: 
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).


References:

  1. National Institutes of Health (.gov) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052875/]
  2. Irritable bowel syndrome: Current therapies and future perspectives by Agata Szymaszkiewicz, Marta ZieliÅ„ska-Antispasmodic-[ScienceDirect(.com)]
  3. Mefenamic Acid-[Drugbank(.com)
  4. Irritable bowel syndrome-[MayoClinic]

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