What are Nonsteroidal Anti-Inflammatory Drugs?

Definition of Nonsteroidal Anti-Inflammatory Drugs

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of medicines that are used in severe to moderate pain situations. These medicines reduce inflammation, pain, and fever. The mechanism of action of these drugs is to block the production of prostaglandins, a chemical responsible for inflammation and pain in the body.[1] 

Also Read- Third Party Manufacturing of medicines

List of common Nonsteroidal Anti-inflammatory drugs:

There are a lot of NSAIDs used in the world, some commonly used NSAIDs are:[2]

1. Aspirin
2. Ibuprofen 
3. Diclofenac Sodium
4. Diclofenac Potassium
5. Naproxen 
6. Celecoxib 
7. Meloxicam 
8. Aceclofenac

Indications for NSAIDs are used:

NSAIDs are used for the following situations and conditions;

• Arthritis
• Headaches
• Muscle aches
• Menstrual cramps
• Toothaches
• Back pain
• Sprains and strains
• Fever

Side effects of Nonsteroidal anti-inflammatory drugs (NSAIDs)

Nonsteroidal anti-inflammatory drugs (NSAIDs) are generally safe and effective when used under the supervision of a healthcare professional. They can harm you if taken as a self-medication practice.

The most common side effects of NSAIDs are gastrointestinal (GI) problems, such as:[3]

1. Indigestion
2. Heartburn
3. Stomach pain
4. Nausea and vomiting
5. Diarrhea
6. Constipation

NSAIDs have the tendency to cause more serious side effects, such as:

1. Stomach ulcers and bleeding
2. Kidney problems
3. Liver problems
4. Cardiovascular problems, such as heart attack and stroke
5. Allergic reactions, such as hives and swelling

References:

1. Phillips WJ, Currier BL. Analgesic pharmacology: II. Specific analgesics. J Am Acad Orthop Surg. 2004 Jul-Aug;12(4):221-33. [PubMed]
2. Medications - non-steroidal anti-inflammatory drugs:[BetterHealth channel]
3. NSAIDs- Side effects of NSAIDs:[NHS(website)]