Dextromethorphan Phenylephrine Chlorpheniramine Maleate Syrup | Ftox-DX Syrup

What is Dextromethorphan, Phenylephrine, and Chlorpheniramine Maleate Syrup?

 Introduction:

The combination of dextromethorphan, Phenylephrine, and Chlorpheniramine (FTOX-DX) is used to treat the cough due to allergies and colds. Dextromethorphan is a cough suppressant that blocks the cough reflex in the brain. Phenylephrine works as a decongestant that narrows the blood vessels in the nose and sinuses which is helpful in relieving nasal congestion. While Chlorpheniramine is an antihistamine in nature. It blocks the effects of histamines, that is responsible for allergic reactions in the body. 

This combination of syrup is used to treat a number of symptoms like cough, runny nose, sneezing, itchy eyes, and sinus congestion. This combination syrup is easily available over-the-counter (OTC). However, It is recommended firmly always consult your doctor before taking this syrup.

Ftox-DX syrup contains dextromethorphan phenylephrine CPM is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies. This is a cough suppressant. Mostly used for dry cough.

What is Dextromethorphan, Phenylephrine, and Chlorpheniramine Maleate Syrup?

Dextromethorphan, Phenylephrine, and chlorpheniramine syrup is a well-trusted and tested combination over the years by physicians. These three different category ingredients work effectively on cough by providing synergic effects. 

Common Brand Names and Variations:

1. Ftox-Dx syrup [Laafon Galaxy Pharmaceuticals]: 1 Variation- ₹92 
2. TusQ-DX [Blue Cross Laboratories Ltd]:  4 Variations- ₹53 to ₹99 
3. Chericof [Sun Pharmaceutical Industries Ltd]: 7 Variations- ₹14 to ₹118
4. Ventryl-D [Micro Labs Ltd]: 2 variants- ₹116
5. Ascorid-D Junior [Glenmark Pharmaceuticals Ltd]: 1 Variation- ₹98

Medical Uses and Benefits of DMR+PE+CPM Syrup:

This combination is a cough suppressant. It is used for dry cough and allergic cough. This medication is also used in post-surgery patients to avoid unnecessary cough, a cough at that time can cause injuries to stitches.

Treating Cough and Cold Symptoms:

It is used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. It is usually taken only for a short time until the symptoms clear up. The cough syrup primarily treats cough symptoms. 

Decongestant Properties of Phenylephrine:

Phenylephrine is a sympathomimetic drug that is very helpful in congestion relief. The main role of phenylephrine is to open nasal congestion. The mechanism of phenylephrine is to stimulate alpha-1 adrenergic receptors in blood arteries that cause vasoconstriction. It works by shrinking blood vessels in the nasal passages and provides relief from congestion. It is also used to open the airways in patients with asthma or COPD. 

Antihistamine Effects of Chlorpheniramine Maleate:

Chlorpheniramine (CPM) is an effective antihistamine, it is used to treat the symptoms of allergies and colds, and coughs. It blocks the effects of histamine. The role of CPM in cough syrup is to deal with symptoms like runny nose, sneezing, Itchy eyes, and cough. 

Chlorpheniramine maleate is an antihistamine that is used to relieve the symptoms of allergies and the common cold. It works by blocking the effects of histamine, a chemical that is released by the body during an allergic reaction.

DEXTROMETHORPHAN  PHENYLEPHRINE CPM SYRUP DOSAGE

Ftox-DX cough syrup contains Dextromethorphan Hbr 10mg.+CPM 2mg.+Phenylephrine HCL 5mg/ 5ml, this medication should take 5 ml twice a day in light cough, it may increase to thrice a day if the cough is in severe condition. Appropriate antibiotics can improve the activity of cough syrup in an allergic cough situation.

Indications and Contraindications

This medication is indicated for the following symptoms:

• Dry Cough
• Runny or stuffy nose
• Sneezing
• Itching and watery eyes
• Sinus congestion
• Sore throat

Appropriate Conditions for Use:

The appropriate conditions for the use of this combination are only advised by a professional medical practitioner. It is highly recommended that do not use this medication as a self-medication. It is not flagged safe by FDA. You should not use this medication under the following conditions:

• Children below 4 years.
• High blood pressure
• Heart disease
• Glaucoma
• Thyroid problems
• Diabetes
• Prostate problems
• Seizure disorder
• Narrow-angle glaucoma
• Liver or kidney disease
• An enlarged prostate
• A blockage in the digestive tract
• A history of drug abuse

Consulting a Healthcare Professional:

The combination of Dextromethorphan, Phenylephrine Hcl, and Chlorpheniramine Maleate is not safe for all patients. It is not flagged as safe medicine without a prescription by the FDA department. You should follow FDA guidelines for unapproved drugs. Always consult a doctor or a healthcare professional before consuming this medicine. 

Contraindications:

This combination may have some drug contradictions because dextromethorphan present in this combination can trigger a histamine release in some patients who are allergic to Dextromethorphan drugs.

This combination should be used under the supervision of a medical practitioner. If anyone feels drowsiness after taking this medication, he should not drive a vehicle or operate machinery which requires mental alertness.

FTOX-DX SYRUP(DMR+PPH+CPM) SIDE EFFECTS :

This combination of dextromethorphan phenylephrine CPM syrup is strong cough formula therefore it may have some side effects if used unnecessarily or asymptomatically. Some common side effects are :

• Diarrhea
• Itching
• Nausea
• Confusion
• Sedation
• Drowsiness
• Dizziness
• Constipation
• Vomiting

PHENYLEPHRINE CHLORPHENIRAMINE DEXTROMETHORPHAN BRAND NAME

There are thousands of brands available in the market for this combination, some popular brands are as:

1. CHERICOF
2. TUSQ-DX
3. FTOX-DX
4. AMIDRYL-DX
5. GLYCODIN
6. ACTICOF
7. ACTIONER-DX
8. ALERNYL-DC
9. ALEX
10. CC CAP NF

Tips for Safe Use and Precautions:

Reading and Understanding the Label:

Read the label carefully before using the syrup. See the cap whether is sealed or broken. Use the dose cap for measuring the quantity of syrup while taking it. Take the quantity as recommended on the label under the dosage heading. 

Storage and Expiry Recommendations:

See the manufacturing and expiry date on the label, if the syrup is expired do not consume it. Store in a cool, dry, and dark place. Keep out of reach of children to avoid any unwanted incidents. 

SHORT DESCRIPTION

Brand Name: FTOX-DX

Dosage Form: Liquid Orals/cough Syrup

Composition:  Dextromethrophan Hbr 10mg.+CPM 2mg.+Phenylephrine HCL 5mg. sorbitol (70%) q.s.

Packing: 100 ML

MRP: Rs. 92.00 PER BOTTLE.

ALSO AVAILABLE: 

FTOX-AM : Ambroxol Hcl 15 mg+Terbutaline Sulphate 1.25mg.+Guaiphenesin 50mg.+menthol 2.5mg./5 ml)

COZICOF-LS : Ambroxol Hcl 15 mg+Levasalbutamol 1mg.+Guaiphenesin 50mg/5 ml

Fonvital Plus: Ginseng with Multivitamins, Minerals & Antioxidants capsules

Mecome-Alpha: Methylcobalamin alpha-lipoic acid pyridoxine Hydrochloride,  folic acid, and Thiamine Mononitrate

DOWN-A SUSPENSION: Aceclofenac and Paracetamol suspension

KUFTIPS SYRUP: An Ayurvedic cough syrup

Itco-200: Itraconazole capsules 200 mg

Laadic-MR Tablet: Diclofenac Potassium, Chlorzoxazone and Paracetamol Tablet.

References:

• SILDEC PE DM- sildec pe dm syrup[https://dailymed.nlm.nih.gov/]
• Chlorpheniramine, dextromethorphan, and Phenylephrine [https://www.drugs.com/mtm/chlorpheniramine-dextromethorphan-and-phenylephrine.html]
• Chlorpheniramine-Dextromethorphan Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing[WebMD]