Hydroquinone Tretinoin & Mometasone cream | Tinto-MH Cream

Hydroquinone Tretinoin & Mometasone cream | Tinto-MH Cream 

Introduction

Tinto-MH cream is a medicated acne and scar cream that contains Mometasone, Hydroquinone, and Tretinoin. It is a topical cream for acne. It is found very effective against black circles around the eyes, scars on the face, acne, redness, itching, and spots. It is a prescription medicine that is also used for the treatment of disease namely melasma. 

Ingredients in Tinto-MH cream

Mometasone Furoate IP     0.10% w/

Hydroquinone             IP    2.0% w/w

Tretinoin                    USP 0.025% w/w

Hydroquinone Tretinoin & Mometasone cream uses

• Treatment of melasma disease
• It is used for the treatment of acne
• Scar, and black circles around the eyes.

How to use Tinto-MH cream:

Take a pie size portion of Tinto-MH cream on your fingertip and apply slowly on the affected places on the face, if black circles around the eyes are persisted then apply the cream on the black circles ensuring that it should not enter the eyes. Do not use it in the daytime. 

Tinto-MH Vs Skinlite cream

Tinto-MH cream and Skinlite cream both are the same combinations of creams. Both products are manufactured in high-quality GMP conditions. The quality of the product is neck to neck the same. The major difference is the MRPs of products. Skinlite Cream has an MRP of Rs. 255 for a 25 gm lami simple tube. Another side of Tinto-MH cream's MRP is Rs. 144/- for a 20 gm stylist lami tube. There is a huge difference in price between both creams. 

Tinto-MH cream supplier offers free delivery on the purchase of 3 tubes. 

Tinto-MH cream substitutes:

There are lots of products that are substitutes for Tinto-MH cream in terms of its composition, but the effectiveness and efficacy of all products are different. Tinto-MH cream is manufactured in special conditions developed for this product only to meet all weather conditions and long-term temperature impacts on the product during storage. The main function of cream is based on the pH maintained by the product which is very important for skin-to-skin. Tinto-MH cream is prepared in such a manner with scientific reasons to adjust with all types of skin orders in India.  Therefore, be assured about adverse effects while using any substitute of Tinto-MH Cream.

Product	Manufacturer	PRICE
Skin Shine Cream	Knoll Pharma	150/15gm
Cosmelite Cream	Oaknet Healthcare Pvt Ltd	304.22/20 gm
Melabest Cream	Mankind Pharma Ltd	193.25/ 15gm
NO SCARS Cream	Torque Pharmaceuticals Pvt Ltd	261.26/ 20gm
Metacortil-Lite Cream	Macleods Pharmaceuticals Pvt Ltd	224.40/15 gm
Skin shine Cream	Cadila Pharmaceuticals Ltd	149.90/15gm
Lomela Cream	Intas Pharmaceuticals Ltd	218/15gm
HHLite Cream	Hegde And Hegde Pharmaceutical LLP	230/20 gm
Melalite XL Cream	Abbott	312.48/15gm
Lookbrite Cream	Torrent Pharmaceuticals Ltd	229/ 20 gm

Studies and Clinical Trials

1. In 2005, a study was carried out by Kircik LH. about Efficacy and Safety of a Triple combination cream in the management of melasma. This study discovered the effectiveness and safety of the cream containing a triple combination of molecules, Mometasone, Tretinoin, and Hydroquinone in the treatment of facial melasma. The results from this study showed significant improvement in the skin pigmentation and overall appearance of the face look with minimum side effects. 
2. Another Study was carried out by Sanchez-Viera M, Imbernon Moya A, and Sanchez-Palencia Ramos in 2010 Jul-Aug, The study involved a double-blind, placebo-controlled study that assessed the efficacy and safety of three-drug combination cream (Mometasone, Tretinoin, and Hydroquinone) in the treatment of Melasma. The results provided significant improvement in the pigmentation on the face and overall face glow was improved, the good thing was not any serious adverse effects were seen.
3. Another study was carried out by Pandya AG, Hynan LS, and Bhore R namely"Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method" in 2011. This study was about to assess the reliability and validity of the Melasma Area and Severity Index (MASI), and the modified MASI scoring method in finding the impact of melasma in patients who were treated with a triple combination of mometasone, hydroquinone, and tretinoin. The Results demonstrated that both scoring methods were credible and valid in evaluating the treatment results.
4. The study carried out in 1975 was known as the "Kligman formula" by Kligman AM, Willis I. A for depigmentation of human skin. Published in Arch Dermatol September 1975. This was a classic study that described the development of a unique cream containing hydroquinone, tretinoin, and a topical steroid for the treatment of hyperpigmentation disorders and melasma. The cream which is known as Kligman Formula is used extensively in various clinical trials and research studies.  

Precautions to take before using Tinto-MH cream:

Avoid contact with eyes, mouth, and mucous membranes. Do not apply the cream during the day and avoid exposing it to sunlight. Exposure to sunlight and U.V. light may cause repigmentation of bleached areas.

Possible side effects of Tinto-MH cream

• Burning and itching at the place of application
• Repigmentation after stopping the use.

Use in pregnancy:

Do not use it during pregnancy.

Genres

• Health & Beauty
• Skincare

Short description of the product

Brand: TINTO-MH

Composition: Mometasone 0.10%w/w, Hydroquinone 2%/w, and Tretinoin 0.025%w/w

Dosage Form: CREAM

PRODUCT LIFE: 2 YEARS

PACK SIZE: 20 GM LAMI TUBE

MRP: 144.80 PER TUBE

Also Available;

FASTER GEL (Linseed Oil 3%, Diclofenac Sodium 1%, Methyl Salicylate 10 %, and Menthol 5% Gel)

LOBULAR-GM: (Clobetasol Propionate 0.5%, Neomycin Sulphate 0.5 %, Miconazole Nitrate  2% Cream.

ITCO-200: (Itraconazole capsules 200 mg)

LOBULAR PLUS: Ofloxacin 0.75%,Ornidazole 2.00%,Itraconazole1.00%, . Clobetasol 0.05%w/w

WhatsApp Number: +91-9812446733

References:

1.  Godse KV. Triple combination of hydroquinone, Tretinoin, and mometasone furoate with glycolic acid peels in melasma. Indian J Dermatol 2009, 54:92-3: URL link
2. Kircik LH. Efficacy and safety of a triple combination cream in the management of facial melasma. Cutis. 2005 Jun;75(6 Suppl):14-7. PMID: 16047963.
3. Sánchez-Viera M, Imbernon-Moya A, Sánchez-Palencia Ramos A, et al. Efficacy and safety of a fixed combination of mometasone furoate, hydroquinone, and tretinoin in the treatment of melasma. Actas Dermosifiliogr. 2010 Jul-Aug;101(6):515-23. PMID: 20646767.
4. Pandya AG, Hynan LS, Bhore R, et al. Reliability assessment and validation of the Melasma Area and Severity Index (MASI) and a new modified MASI scoring method. J Am Acad Dermatol. 2011 Jul;65(1):e89-96. PMID: 21679812.
5. Kligman AM, Willis I. A new formula for depigmenting human skin. Arch Dermatol. 1975 Sep;111(9):40-8. PMID: 1154152.

Disclosure: 

As a pharmaceutical professional involved in manufacturing different types of medicines including creams and ointment. I do not have any personal interests or conflicts of interest. However, it is possible that the information consumed by me as a reference for this post is based on the available scientific research and publication in the public domain and on the internet. There are possibilities of being the information biased by some pharmaceutical companies who funded the studies. Therefore, it is important to critically evaluate the source of information. 

I have assessed and reviewed several studies from reputed sources and websites to support the authenticity of the information provided. The sources were selected on the basis of the relevancy and authority of the websites in the niche. If you require additional information, please let me know by leaving a comment and I will do my best to provide it to you.