Pantoprazole gastro-resistant and Domperidone prolonged release capsules IP | Pantafon-DSR

Introduction:

Embarking on a quest for optimal digestive health requires informed decision-making, especially when considering medications like Pantoprazole (IR) and Domperidone SR capsules (Pantafon-DSR). In this comprehensive guide, we will touch on all aspects of these two molecules of FDC medicine, exploring their mechanisms of action, efficacy, safety profiles, and more. Whether you're seeking relief from acid-related disorders or addressing gastrointestinal (GERD) motility concerns, join us on this journey as we compare and contrast Pantoprazole (IR) and Domperidone SR capsules, helping you make choices aligned with your unique health needs. 

Understanding Pantoprazole (IR) and Domperidone SR: 

Pantoprazole:

Pantoprazole is renowned for its effectiveness in managing acid-related disorders like GERD. Its mechanism of action involves reducing stomach acid production, providing relief from conditions like acid reflux and peptic ulcers.

Domperidone:

On the other hand, Domperidone (Sustained release form) focuses on enhancing gastrointestinal motility. In combination with PPIs (Pantoprazole or Rabeprazole), the role of Domperidone is to help the PPI mechanism of action with the aid to reflux of acid by improving the spinters, It aids in the movement of food through the digestive system, making it a valuable option for those facing mobility issues.

Efficacy and Effectiveness:

When considering the efficacy of Pantoprazole DSR, Pantoprazole (IR) excels in controlling acid-related symptoms, providing quick relief. Domperidone SR, however, acts to address motility concerns and promotes smooth digestion.

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Safety Profile: 

Pantoprazole: Pantoprazole is generally well-tolerated, Pantoprazole may have side effects such as nausea or headache. It's important to follow the recommended guidelines of medical professionals to overcome possible risks.

Domperidone: Domperidone SR comes with its set of precautions, including potential interactions with other medications. Understanding its safety profile is crucial for minimizing risks such as cardiovascular and heartbeat-related issues.

Dosage and Administration;

Pantoprazole:

Oral: 40 mg orally once a day

Duration of therapy: 8 weeks

Parenteral: 40 mg via IV infusion once a day, given over at least 2 minutes OR over 15 minutes

Duration of therapy: 7 to 10 days

Domperidone SR: 

Domperidone SR is often taken before meals as well, with dosage recommendations tailored to individual needs. Strict adherence to administration instructions is advised. The usual dose of Domperidone is 10mg thrice a day or 30 mg in Sustained-release form.

Interactions and Contradictions:

Pantoprazole: 

Be aware of potential drug interactions involving Pantoprazole, especially if you are on other medications like heart or diabetes, etc. Always consult your healthcare provider before initiating any new medication in your routine.

Domperidone: Similarly, Domperidone SR may interact with certain drugs. Ensuring your healthcare provider is aware of all medications is crucial to prevent complications.

Pantoprazole gastro-resistant and Domperidone prolonged-release capsules uses;

Pantafon-DSR Capsules containing Pantoprazole are used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. It is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults. Pantoprazole is in a class of medications called proton-pump inhibitors.

PANTAFON-DSR SPECIFICATIONS;

Pantoprazole and Domperidone DSR capsules are manufactured by WHO-GMP certified company, Packing the latest trending alu alu, Shining dripoff box pack.

Ethical Brand used all over India by Reputed Doctors. Brand Name: PANTAFON-DSR

Dosage Form: Capsule

Composition: Each Hard gelatin capsule contains:

Pantoprazole Sodium IP eq. to Pantoprazole 40 mg & Domperidone IP 30 mg ( 10 mg as Immediate release and 20 mg as sustained-release granules).

Packing 10*10 alu alu

MRP: 110.00

Summary:

In the journey toward optimal digestive health, knowledge is your most potent ally. Prepared with insights into the mechanisms, efficacy, safety profiles, and patient suitability of Pantoprazole (IR) and Domperidone SR, you are in a better position to engage in meaningful discussions with your healthcare provider.

In conclusion, whether you find relief in the acid-suppressing capabilities of Pantoprazole (IR) or the motility-enhancing benefits of Domperidone SR, the key lies in collaboration with your healthcare team. Pantoprazole-DSR capsules are a strong option for GERD and stomach acid-related symptoms

Also Available;

• Rebfon-DSR (Rabeprazole 20mg +Domperidone 30mg)
• Fonvital Plus: Ginseng with Multivitamins, Minerals & Antioxidants capsules
• Mecome-Alpha: Methylcobalamin alpha-lipoic acid pyridoxine Hydrochloride,  folic acid, and Thiamine Mononitrate
• DOWN-A SUSPENSION: Aceclofenac and Paracetamol suspension
• KUFTIPS SYRUP: An Ayurvedic cough syrup
• Itco-200: Itraconazole capsules 200 mg

Disclaimer:

Disclaimer: This site's information and articles are for educational purposes only. The information given here should not be used for the diagnosis or treatment of any health problem or disease without expert advice. The advice of a qualified medical practitioner should always be sought for medical examination and treatment.

References:

1. Pantoprazole: a proton pump inhibitor-
PMID: 19938880, DOI: 10.2165/1153121-S0-000000000-00000-[National Library of Medicines]
2. Efficacy and Safety of Domperidone in Combination with Proton Pump Inhibitors in Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis of Randomised Controlled Trials[PMC-PubMed Central]
3. Cardiovascular Safety Profile and Clinical Experience With High-Dose Domperidone Therapy for Nausea and Vomiting- Arleen Ortiz, MD, Chad J. Cooper, MD, MHA, Alicia Alvarez, MD, Yvette Gomez, BS, Irene Sarosiek, MD, and Richard W. McCallum, MD-[PMC-PubMed Central]
4. 5 Pantoprazole Interactions You Should Know About-[GoodRx Health]
5. Domperidone drug interactions-Drugs and Supplement-Domperidone (oral route)-[MayoClinic(.org)]

Reviewed by;

Dr. Yogesh Chaudhary (B. Pharma)

Senior Pharmacist at S.N. Medical College, Agra-(UP)