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Lace-SP is aceclofenac Paracetamol and serratiopeptidase tablet which is used for pain relief. It also relieves pain in conditions like headache, mild migraine, musculoskeletal pain, or painful menses, Lace-SP orange colored is film-coated tablet. Served in elegance alu alu packing.

Aceclofenac Paracetamol and Serratiopeptidase uses:

Lace-SP Aceclofenac Paracetamol and Serratiopeptidase Tablet are used for pain relief. It also relieves pain in conditions like headache, mild migraine, musculoskeletal pain, or painful menses, It is very helpful in the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis in adults



Serratiopeptidase (Serratia E-15 protease, also known as serralysin, serrapeptase, serratiapeptase, Serratia peptidase, serratiopeptidase, or serrapeptidase), is a proteolytic enzyme (protease) produced by non-pathogenic enterobacteriumSerratia sp. E-15, now known as Serratia marcescens ATCC 21074. This microorganism was originally isolated in the late 1960s from silkworm bombyx Mori L. (intestine), Serratiopeptidase is present in the silkworm intestine and allows the emerging moth to dissolve its cocoon. Serratiopeptidase is produced by purification from the culture of Serratia E-15 bacteria. It is a member of the Peptidase M10B (Matrixin) family.


Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) analog of diclofenac. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.

Aceclofenac was patented in 1983 and approved for medical use in 1992.

Chemistry of Aceclofenac –

Aceclofenac (C16H13Cl2NO4), chemically [(2-{2, 6-dichlorophenyl) amino} phenylacetooxyacetic acid], is a crystalline powder with a molecular weight of 354.19. It is practically insoluble in water with good permeability. It is metabolized in human hepatocytes and human microsomes to form [2-(2′,6′-dichloro-4′-hydroxy- phenylamino) phenyl] acetoxyacetic acid as the major metabolite.


Paracetamol, also known as acetaminophen, is a medication used to treat pain and fever. It is typically used for mild to moderate pain relief. Evidence is mixed for its use to relieve fever in children. It is often sold in combination with other medications, such as in many cold medications. Paracetamol is also used for severe pain, such as cancer pain and pain after surgery, in combination with opioid pain medication. It is typically used either by mouth or rectally but is also available by injection into a vein. Effects last between two and four hours

Paracetamol is generally safe at recommended doses. The recommended maximum daily dose for an adult is three to four grams. Higher doses may lead to toxicity, including liver failure. Serious skin rashes may rarely occur. It appears to be safe during pregnancy and when breastfeeding. In those with liver disease, it may still be used, but in lower doses. It is classified as a mild analgesic. It does not have significant anti-inflammatory activity. How it works is not entirely clear.

Paracetamol was first made in 1877. It is the most commonly used medication for pain and fever in both the United States and Europe. It is on the World Health Organization’s List of Essential Medicines. Paracetamol is available as a generic medication, with brand names including Tylenol and Panadol among others. The wholesale price in the developing world is less than US$0.01 per dose. In the United States, it costs about US$0.04 per dose. In 2017, it was the 25th-most commonly prescribed medication in the United States, with more than 24 million prescriptions.

Lace-SP- Indication

Aceclofenac Paracetamol and serratiopeptidase tablet have the following Indications:

  • Fever and flu
  • Bone and joint pain
  • Rheumatoid Arthritis
  • Osteoarthritis
  • Headache
  • Mild migraine pain
  • Toothache
  • Ankylosing spondylitis
  • Menstrual pain
  • Cold and sore throat
  • Inflammation (swelling)

Lace-SP Possible Side-effects:

These are some side-effects that may be associated with Aceclofenac Paracetamol and serratiopeptidase tablet

  • Abdominal pain
  • Dizziness
  • Emesis (vomiting)
  • Dyspepsia (indigestion)
  • Allergic reaction (skin redness and rashes)
  • Loss of appetite
  • Hepatic (liver) damage
  • Kidney Failure


LACE-SP i.e. Aceclofenac Paracetamol and Serratiopeptidase Tablet is covered in Schedule H Drugs, Since Schedule H  Medicines are adviced to take only after Doctor’s prescriptions so that should not take this medicine from your own decision. This combination contains three medicaments which all have many drugs Intractions and possible reaction chances should not use without prescription.

  • Women in pregnancy and lactation should not take.
  • Since this combination have slightly sedative properties do not take it  prior to driving
  • Do not co-administer with alcohol
  • In Gastric Ulcer should not use.
  • Should not use in asthma


Aceclofenac Paracetamol and Serratiopeptidase tablets brand names:

Ipca Laboratories Ltd
Lupin Ltd
Cipla Ltd
Wockhardt Ltd
Mankind Pharma Ltd

Short Description


Composition: Aceclofenac 100mg. + Paracetamol 325mg..+Serratiopeptidase 15mg.

Packing: 10*1*10 Alu Alu


MRP: Rs. 85.00

Also Available;

LACE-P TABLET (AceclofenacParacetamol Tablets)

Down-A Susp (AceclofenacParacetamol suspension)

LAADIC-SP TABLET (Diclofenac+Paracetamol+Serratiopeptidase)



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