Dosycal Plus Softgel capsules are consist of Calcitriol, Calcium Carbonate, and Zinc Sulphate. Calcitriol usually used in patients with kidney disease who are unable to make enough of the active form of Vitamin D. Dosycal Plus is also used to prevent and treat certain types of calcium/phosphorus/parathyroid problems that can happen with long-term kidney dialysis or hypoparathyroidism
Dosycal Plus Softgel contains Calcitriol along with calcium and zinc. Calcitriol increases blood calcium levels (Ca2+) by promoting absorption of dietary calcium from the gastrointestinal tract and increasing renal tubular reabsorption of calcium thus reducing the loss of calcium in the urine. DOSYCAL PLUS Calcitriol is used to prevent low levels of calcium in the body and also helps in bone disease in patients who have kidney disease or parathyroid glands.
USES OF DOSYCAL PLUS CALCITRIOL:
Calcitriol is prescribed for:
- Treatment of hypocalcemia – hypoparathyroidism, osteomalacia (adults), rickets(infants, children), renal osteodystrophy, chronic kidney disease
- Treatment of osteoporosis
- Prevention of corticosteroid-induced osteoporosis
Calcitriol has been used in an ointment for the treatment of psoriasis, although the vitamin D analog calcipotriol (calcipotriene) is more commonly used. Calcitriol has also been given by mouth for the treatment of psoriasis and psoriatic arthritis. Research on the nonacademic actions of calcitriol and other VDR-ligand analogs and their possible therapeutic applications has been reviewed
Mechanism of action Of Calcitriol:
Calcitriol maintains the level of calcium in the blood, promotes the absorption of dietary calcium gastrointestinal tract. Increase the renal tubular reabsorption of calcium, which reduces calcium loss. Stimulates the calcium release from bones.
Brand Name: DOSYCAL PLUS SOFT GELS
Dosage Form: Soft Gelatin Capsules
Composition: Calcitriol 0.25 mcg.+Calcium Carbonate 500mg+Zinc7.5mg.
Packing: 10*1*10 Blister
MRP: Rs. 126.00 PER 10 SOFT GELS
The author has 18 years of experience in the Quality Control, and Quality Assurance departments of Pharmaceutical Manufacturing Companies. Have exposure of all documents for WHO-GMP audits, Export documents, US-FDA documents, Validation of Pharma machinery, and Quality Control Instruments.